Effect of inflammation on HDL structure and function
KR Feingold, C Grunfeld - Current opinion in lipidology, 2016 - journals.lww.com
KR Feingold, C Grunfeld
Current opinion in lipidology, 2016•journals.lww.comDuring inflammation multiple changes in HDL structure occur leading to alterations in HDL
function. In the short term, these changes may be beneficial resulting in an increase in
cholesterol in peripheral cells to improve host defense and repair but over the long term
these changes may increase the risk of atherosclerosis.
function. In the short term, these changes may be beneficial resulting in an increase in
cholesterol in peripheral cells to improve host defense and repair but over the long term
these changes may increase the risk of atherosclerosis.
Summary
During inflammation multiple changes in HDL structure occur leading to alterations in HDL function. In the short term, these changes may be beneficial resulting in an increase in cholesterol in peripheral cells to improve host defense and repair but over the long term these changes may increase the risk of atherosclerosis.
Lippincott Williams & Wilkins